H2N2V1, Main, Exploration, bibRecord, 002704

Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin.

Identifieur interne : 002704 ( Main/Exploration ); précédent : 002703; suivant : 002705

Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin.

Auteurs : R B Armstrong ; G M Butchko ; S C Kiley ; M A Phelan ; F A Ennis

Source :

Infection and immunity [ 0019-9567 ] ; 1981.

RBID : pubmed:7298178

Descripteurs français

KwdFr :
- Activation des lymphocytes, Glycoprotéines (pharmacologie), Hémagglutinines virales, Mitogènes, Orthomyxoviridae (immunologie), Protéines virales (pharmacologie), Virus de la grippe A (immunologie).
MESH :
- immunologie : Orthomyxoviridae, Virus de la grippe A.
- pharmacologie : Glycoprotéines, Protéines virales.
- Activation des lymphocytes, Hémagglutinines virales, Mitogènes.

English descriptors

KwdEn :
- Glycoproteins (pharmacology), Hemagglutinins, Viral, Influenza A virus (immunology), Lymphocyte Activation, Mitogens, Orthomyxoviridae (immunology), Viral Proteins (pharmacology).
MESH :
- chemical , pharmacology : Glycoproteins, Viral Proteins.
- chemical : Hemagglutinins, Viral, Mitogens.
- immunology : Influenza A virus, Orthomyxoviridae.
- Lymphocyte Activation.

Abstract

The hemagglutinin glycoprotein is responsible for the mitogenic effect of influenza A viruses of the H2N2 subtype. This was indicated by the ability of viruses bearing the H2-hemagglutinin glycoprotein, regardless of its associated neuraminidase, to induce lymphocyte proliferation in normal spleen cell suspensions and by the ability of antisera with specificity for the H2-hemagglutinin to block this response. Moreover, purified hemagglutinin from representative viruses from the H0N1, H1N1, H2N2, H3N2, and influenza B subtypes were also shown to be mitogenic.

PubMed: 7298178

Affiliations:

Le document en format XML

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<author><name sortKey="Butchko, G M" sort="Butchko, G M" uniqKey="Butchko G" first="G M" last="Butchko">G M Butchko</name>
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<author><name sortKey="Kiley, S C" sort="Kiley, S C" uniqKey="Kiley S" first="S C" last="Kiley">S C Kiley</name>
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<author><name sortKey="Phelan, M A" sort="Phelan, M A" uniqKey="Phelan M" first="M A" last="Phelan">M A Phelan</name>
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<author><name sortKey="Ennis, F A" sort="Ennis, F A" uniqKey="Ennis F" first="F A" last="Ennis">F A Ennis</name>
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<series><title level="j">Infection and immunity</title>
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<term>Influenza A virus (immunology)</term>
<term>Lymphocyte Activation</term>
<term>Mitogens</term>
<term>Orthomyxoviridae (immunology)</term>
<term>Viral Proteins (pharmacology)</term>
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<term>Glycoprotéines (pharmacologie)</term>
<term>Hémagglutinines virales</term>
<term>Mitogènes</term>
<term>Orthomyxoviridae (immunologie)</term>
<term>Protéines virales (pharmacologie)</term>
<term>Virus de la grippe A (immunologie)</term>
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<keywords scheme="MESH" type="chemical" qualifier="pharmacology" xml:lang="en"><term>Glycoproteins</term>
<term>Viral Proteins</term>
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<term>Mitogens</term>
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<keywords scheme="MESH" qualifier="immunologie" xml:lang="fr"><term>Orthomyxoviridae</term>
<term>Virus de la grippe A</term>
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<keywords scheme="MESH" qualifier="immunology" xml:lang="en"><term>Influenza A virus</term>
<term>Orthomyxoviridae</term>
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<term>Protéines virales</term>
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<front><div type="abstract" xml:lang="en">The hemagglutinin glycoprotein is responsible for the mitogenic effect of influenza A viruses of the H2N2 subtype. This was indicated by the ability of viruses bearing the H2-hemagglutinin glycoprotein, regardless of its associated neuraminidase, to induce lymphocyte proliferation in normal spleen cell suspensions and by the ability of antisera with specificity for the H2-hemagglutinin to block this response. Moreover, purified hemagglutinin from representative viruses from the H0N1, H1N1, H2N2, H3N2, and influenza B subtypes were also shown to be mitogenic.</div>
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Serveur d'exploration H2N2

Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin.

Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki

	Serveur d'exploration H2N2
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